This is an excellent review of hyperpigmentation and melanoma, with an emphasis novel treatments for correction. Melasma involves a dysregulation of melanocytes that is not evenly distributed across the facial plane. The authors note that some of the causes of melasma include “hyperactive melanocytes, hormonal stimulation, UV-induced oxidative stress, dermal inflammation, fibroblast senescence, and pigmentary incontinence.” The concepts of dermal inflammation and pigmentary incontinence are less discussed among dermatologists, but seem to be strong factors leading to uneven hyper pigmented skin.
Treatment algorithms discussed include “ low-fluence picosecond lasers, fractional CO2 laser-assisted drug delivery, chemical peel hybrids, and exosome-augmented microneedling-offer enhanced pigment clearance with improved safety profiles.” The authors note a high risk of relapse.
In our Santa Monica plastic surgery and dermatology office, our clinicians include board certified plastic surgeons and board certified dermatologists. We offer laser, chemical peel, and exfoliative treatments to help correct melasma. Microneedling and Melasma peels continue to be a major focus for correction; as is topical skincare regimens such as Melarase+ to help reduce pigmentary load.
Schedule a consultation in our Santa Monica office for melasma treatment. We offer microneedling RF, microneedling with exosomes or PRP, laser therapy, and chemical peels to reduce pigmentation. Our Melarase+ topical formulation can help reduce pigmentary deposition and is used once to twice daily.
Raffy Karamanoukian, MD FACS
RF Microneedlng in Santa Monica
www.karesurgery.com
Los Angeles
(310) 998-5533
#pacificpalisadeslabiaplasty #pacificpalisadesplasticsurgery #santamonicaplasticsurgery #santamonicalabiaplasty