Fat grafting is an important cosmetic surgery adjunct used to volumize soft tissue of the face and body. In terms of breast cancer reconstruction, fat grafting is useful to restore natural soft tissue balance overlying breast implants. Survival of transferred fat is a priority; as increased survival reduces the physical and emotional burden on patients and improves longterm results.
This study design assessed whether enhancement of a fat transfer volume with PLLA poly-lactic acid could increase survival. Researchers first transferred fat using a rat model and compared the viability of the fragmented fat with Group 3 which combined the fat with PLLA in a one to one ratio.
Results demonstrated that PLLA could reduce inflammatory and necrotic changes and improve volume retention, when compared to fragmented fat transferred without PLLA.
These findings, although preliminarily performed using an animal model, lend support to the novel use of PLLA as a fat transfer booster. Reduction in inflammation and necrosis is a very positive finding and may be incorporated in cosmetic surgery use in the future.
Raffy Karamanoukian, MD FACS
Fat Grafting and Fat Transfer
www.karesurgery.com
Los Angeles
(310) 998-5533
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