Kare Plastic Surgery & Skin Health Center · Santa Monica & Los Angeles
Botox for Underarm Sweating
Santa Monica
804 7th Street, Santa Monica, CA 90403 · Near Montana Avenue · (310) 998-5533
FDA-approved Botox for axillary hyperhidrosis stops excessive underarm sweating for up to 12 months in a 15-minute appointment. Board-certified dermatologist Dr. Tiffany Sierro at Kare Plastic Surgery in Santa Monica
Call (310) 998-5533 Request a Consultation
FDAApproved Since 2004
81%Patients Achieve >50% Sweat Reduction
Botox for Underarm Sweating Santa Monica
Stop Excessive Sweating — Up to 12 Months Per Treatment
Dr. Tiffany Sierro, MD Board-Certified Dermatologist Hyperhidrosis Treatment · Botox for Excessive Sweating · Sweat Mapping Protocol · Kare Plastic Surgery & Skin Health Center, Santa Monica
Hyperhidrosis — the medical term for excessive sweating beyond what the body needs for temperature regulation — affects approximately 15 million Americans and significantly impairs daily life for those who experience it. Stained clothing, social embarrassment, limited wardrobe choices, and the constant anxiety of visible sweat marks are not character flaws or hygiene failures. They are the predictable consequences of overactive sweat glands that respond to nerve signals even when the body has no physiological need to cool itself.
At Kare Plastic Surgery & Skin Health Center at 804 7th Street in Santa Monica near Montana Avenue, board-certified dermatologist Dr. Tiffany Sierro, MD treats axillary hyperhidrosis with FDA-approved Botox — the most clinically validated, most patient-satisfying, and most precisely targeted treatment available for excessive underarm sweating. The mechanism is precise: Botox temporarily blocks the release of acetylcholine, the neurotransmitter that triggers sweat gland activation. When acetylcholine cannot be released, the nerve signal never reaches the sweat gland — and the sweat simply does not happen. One treatment. Up to 12 months of complete dryness.
✅ FDA Approved Botox (botulinum toxin type A) for severe primary axillary hyperhidrosis — approved July 19, 2004. Used in more than 1 million patients worldwide for hyperhidrosis treatment.
81%Of patients achieve >50% sweat reduction in clinical trial (n=322)
50%Of patients had results lasting 201+ days (nearly 7 months)
15 moSome patients report dryness lasting up to 14–16 months
50Units per armpit — typical therapeutic dose
Hyperhidrosis Services at Kare Skin Health Center Santa Monica
- Botox for axillary (underarm) hyperhidrosis — FDA-approved
- Botox for palmar (hand) hyperhidrosis — higher dose protocol
- Botox for plantar (foot) hyperhidrosis
- Botox for craniofacial hyperhidrosis (scalp, forehead)
- Sweat mapping (starch-iodine Minor’s test) for treatment planning
- Alternative neurotoxins: Daxxify, Xeomin for eligible patients
- Insurance pre-authorization assistance for medically indicated cases
Kare Skin Health Center · Santa Monica · Near Montana Avenue
Excessive underarm sweating?
The Dr. Sierro Protocol
Botox Hyperhidrosis Treatment at Kare Plastic Surgery
Hyperhidrosis Evaluation & Diagnosis
Dr. Sierro performs a comprehensive hyperhidrosis evaluation — distinguishing primary hyperhidrosis (no underlying cause, genetic predisposition, typically beginning in adolescence) from secondary hyperhidrosis (resulting from medications, hormonal changes, or systemic conditions requiring evaluation before treatment). The evaluation includes a quality-of-life impact assessment using the Hyperhidrosis Disease Severity Scale (HDSS) to confirm that the sweating meets the threshold for medically indicated treatment.
Sweat Mapping with Minor’s Starch-Iodine Test
The iodine-starch test (Minor’s test) — a painless diagnostic procedure in which a solution is applied to the underarm and a starch powder placed over it that turns dark blue or purple in areas of active sweating — precisely maps the distribution and intensity of each patient’s hyperhidrosis zone before the injections are planned. This sweat map determines the injection grid placement, the total Botox dose, and the specific concentration needed — producing a personalized injection plan rather than a templated protocol.
Botox Injections — 15 to 30 Minutes
The mapped underarm area is divided into a grid with injection points spaced approximately 1–2cm apart across the hyperhidrotic zone. Topical anesthetic cream is applied 30–45 minutes before the procedure; ice cooling is used immediately before each injection to minimize discomfort. The standard dose is 50 units of Botox per axilla (100 units total), though Dr. Sierro adjusts the dose based on the sweat map findings and the degree of hyperhidrosis severity. The procedure takes 15–30 minutes total. Patients return to normal activity immediately.
Onset & Duration — 3 to 7 Days to Full Effect
Patients typically notice a significant decrease in sweating within 3–7 days of treatment, with full dryness developing over 2 weeks. Most patients experience 7–12 months of dramatically reduced sweating before follow-up treatment is required — significantly longer than the 3–4 month duration of Botox for facial wrinkles. Dr. Sierro schedules follow-up treatment when sweating begins to return, typically at 7–16-month intervals.
Botox for Hyperhidrosis Beyond the Underarms
Palmar (Hands)
Excessive hand sweating — particularly debilitating for professional, social, and romantic interactions. Higher Botox dose required due to increased sweat gland density. Most effective when treated in combination with axillary hyperhidrosis.
foot sweating
Excessive foot sweating causing maceration, fungal infections, and odor. Botox for plantar hyperhidrosis requires topical anesthesia due to higher sensitivity of the plantar skin. Duration tends to be longer than axillary treatment.
scalp sweating
Excessive scalp or forehead sweating causing visible dripping during meetings, exercise, or heat exposure. Botox for craniofacial hyperhidrosis is less common but highly effective, with results lasting 6–12 months per treatment cycle.
“Hyperhidrosis can significantly affect quality of life. Botox treatments can quickly improve excess sweating.”
Kare Skin Health Center, Santa Monica
Insurance coverage for Botox hyperhidrosis treatment: Botox for severe primary axillary hyperhidrosis is covered by many PPO insurance plans when the patient has documented failure of prescription-strength antiperspirant therapy. Dr. Sierro provides the medical documentation and prior authorization support needed for insurance claims. Call (310) 998-5533 to discuss your coverage before scheduling.
Frequently Asked Questions
Where can I get Botox for underarm sweating in Santa Monica?
Kare Plastic Surgery at 804 7th Street in Santa Monica near Montana Avenue offers FDA-approved Botox for axillary hyperhidrosis by board-certified dermatologist Dr. Tiffany Sierro. The procedure takes 15–30 minutes and produces up to 12 months of dryness. Clinical studies show 81% of patients achieve greater than 50% reduction in sweating. Call (310) 998-5533. We serve patients from Santa Monica, Beverly Hills, Brentwood, Pacific Palisades, Malibu, and all of Los Angeles.
Is Botox for sweating different from Botox for wrinkles?
The Botox molecule is the same — botulinum toxin type A — but the dilution, dose, injection pattern, and target are different. For hyperhidrosis, the Botox is diluted more for wider distribution across the sweat gland field, injected at a larger number of superficial points, and dosed at approximately 50 units per armpit rather than the smaller doses used for individual facial muscle groups.
Is Botox for hyperhidrosis safe?
Botox for axillary hyperhidrosis received FDA approval in 2004 and has since been administered to millions of patients worldwide with an excellent safety profile. Side effects are typically mild and localized — slight bruising, temporary tenderness, or minimal swelling at the injection sites that resolves within days. The treated area ceases sweating, but the body’s overall thermoregulation is not impaired — other sweat glands throughout the body fully maintain normal temperature control. Compensatory hyperhidrosis (increased sweating at other sites) is very rarely reported after axillary Botox alone.
Related Resources at Kare Plastic Surgery
Kare Plastic Surgery & Skin Health Center · Santa Monica · Near Montana Avenue
Schedule a Hyperhidrosis Consultation
Schedule a Botox hyperhidrosis consultation with Dr. Tiffany Sierro, board-certified dermatologist at Kare Skin Health Center in Santa Monica — FDA-approved treatment for underarm, hand, foot, and scalp hyperhidrosis with sweat mapping, personalized dosing, and insurance pre-authorization support.